Medicines, called anabolic steroids contain METHANDIENONE.
You start lifting double the weights. Your weight increases by about ten kgs in the right places. You feel GOOD the whole day and feel FRESH on waking up. Your sexual drive DECREASES.
BODY BUILDING BRINGS TO MIND ONE NAME ARNOLD SWARZENEGGER.
Body building craze catches teenage boys. They often join a gymnasium. Word spreads around that there is a medicine that can increase biceps and give fullness and shape to body muscles. Like the macho cinema hero. Did you say Arnold Swarcheneggar?
a]
Main risks and target organs
There is no serious risk from acute poisoning, but.
chronic use can cause harm. The main risks are those of
excessive androgens: menstrual irregularities and
virilization in women and impotence, premature cardiovascular
disease and prostatic hypertrophy in men. Both men and women
can suffer liver damage with oral anabolic steroids
containing a substituted 17-alpha-carbon. Psychiatric changes
can occur during use or after cessation of these
agents.
b]
Summary of clinical effects
Acute overdosage can produce nausea and gastrointestinal.
upset. Chronic usage is thought to cause an increase in
muscle bulk, and can cause an exageration of male
characteristics and effects related to male hormones.
Anabolic steroids can influence sexual function. They can
also cause cardiovascular and hepatic damage. Acne and male-
pattern baldness occur in both sexes; irregular menses,
atrophy of the breasts, and clitoromegaly in women; and
testicular atrophy and prostatic hypertrophy in men..
c]
Main adverse effects
The adverse effects of anabolic steroids include weight.
gain, fluid retention, and abnormal liver function as
measured by biochemical tests. Administration to children can
cause premature closure of the epiphyses. Men can develop
impotence and azoospermia. Women are at risk of
virilization.
d]
USES.
Indications
Anabolic agent; systemic
Anabolic steroid
Androstan derivative; anabolic steroid
Estren derivative; anabolic steroid
Other anabolic agent
Anabolic agent for systemic use; veterinary
Anabolic steroid; veterinary.
Estren derivative; veterinary
e]
Description
The only legitimate therapeutic indications for
anabolic steroids are:
(a) replacement of male sex steroids in men who have.
androgen deficiency, for example as a result of loss
of both testes
(b) the treatment of certain rare forms of aplastic
anaemia which are or may be responsive to anabolic
androgens.
(ABPI Data Sheet Compendium, 1993)
(c) the drugs have been used in certain countries to.
counteract catabolic states, for example after major
trauma.
Source:
AUTHOR(S), REVIEWER(S), DATE(S) (INCLUDING UPDATES), COMPLETE
ADDRESS(ES)
Author: Dr R. E. Ferner,
West Midlands Centre for Adverse Drug Reaction.
Reporting,
City Hospital Dudley Road,
Birmingham B18 7QH
England.
Tel: +44-121-5074587
Fax: +44-121-5236125
Email: fernerre@bham.ac.uk
.
Date: 1994
Peer review: INTOX Meeting, Sao Paulo, Brazil, September 1994
(Drs P.Kulling, R.McKuowen, A.Borges, R.Higa,
R.Garnier, Hartigan-Go, E.Wickstrom)
Editor: Dr M.Ruse, March 1998
http://www.inchem.org/.
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